Forgotten Super Heroes of Science and Medicine: Choh Hao Li

The Society of American Archivists’ Science, Technology and Health Care roundtable recently launched a project to highlight “underrepresented and diverse persons and groups in collections of the history of science, technology and health care.” The section is calling this endeavor the “Forgotten Super Heroes of Science and Medicine.” UCSF Archives & Special Collections will be contributing to this project by periodically posting to the blog regarding these heroes. This is our first installment.

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Biochemist Choh Hao Li was among the first to synthesize the human growth hormone and later discovered beta-endorphin. Born in 1913 in Guangzhou, China, Li graduated from the University of Nanjing before moving to the US to attend graduate school at UC Berkeley in 1935. Upon earning his Ph. D. in Organic Chemistry in 1938, Li began working on the UC Berkeley campus at the Institute of Experimental Biology with Herbert McLean Evans. In 1950, Li became the first director of the newly created Hormone Research Laboratory. He moved with the laboratory to UCSF in 1967, where Li worked until his retirement in 1983. As an emeritus professor at UCSF, Li then established the Laboratory of Molecular Endocrinology, where he remained director until his death in 1987.

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Dr. Li spent most of his career studying the functions of the pituitary gland, which is located at the base of the brain and controls many of the body’s functions.  At the Institute of Experimental Biology, Li first began his attempts to isolate and identify the anterior pituitary hormones; he was eventually able to isolate and purify six of the eight known hormones secreted. It wasn’t until the early 1970s, when heading the Hormone Research Laboratory, that Li was able to actually synthesize human growth hormone. Later that decade, Li discovered beta-endorphin, a neuropeptide that acts as a pain killer. Before his retirement, Li was also able to synthesize insulin-like growth factor 1, a protein that mediates the effects of growth hormone. During his lifetime, Li published over 1100 scientific articles, was given many awards, including the Albert Lasker Award for Basic Medical Research, and was nominated at least twice for the Nobel Prize.

The Choh Hao Li papers are open for research at UCSF Archives & Special Collections: http://www.oac.cdlib.org/findaid/ark:/13030/tf738nb543/

Digitized State Medical Journals: Searching “Alcohol” and “Prohibition”

This is a guest post by Sophia Lahey, UCSF Archives and Special Collections Intern.

Recently, as part of a larger UCSF Archives and Special Collections digitization project, over 200 medical journals from various state medical associations were digitized and added to the Internet Archive. In order to ensure scan quality, I sifted through thousands of pages to make sure everything was clear enough so that the search function would work properly. As long as the scans are clean, you can search for any word in the entire collection! For instance, I searched the words “alcohol” and “prohibition” and came up with some fascinating results.

The first items that struck me when I started to read through the journals were the ads. In addition to the articles, the ads serve as evidence for historians about how people lived, what was socially acceptable, and what they were interested in buying. In these journals, most of the ads were geared towards doctors, advertising things like medicine, medical instruments, insurance, and even computer management systems.

This ad for Dentocain Teething Lotion is from the 1950s. The infant teething medication advertised is 70% alcohol and includes chloroform!  By modern medical standards, this product would definitely raise some red flags. As I kept looking through more journals, I noticed that the older ones featured alcohol in many of the medicines advertised.

In this ad, though the ingredients aren’t listed, you can see on the bottle that the medicine contains 7 1/2% alcohol. The ad was published in 1927, during prohibition. So how could medicine contain alcohol when it was illegal? Well, alcohol could still be prescribed by a doctor. Like other medications, a doctor had to fill out a prescription in order for a patient to get items, like whiskey, for medicinal reasons.

Some doctors wrote prescriptions for liquor off record and for a profit. This created a controversy – government legislation vs. the rights of the practitioner to prescribe as much as he or she felt was needed. This lead to court cases as well as strongly worded opinion pieces about said court cases and ethics in the medical community. These opinion pieces as well as other news stories can be read in the medical journals in the UCSF collection.

An Old-Fashioned Expedition into the Vault

This is a guest post by Kristin Daniel, UCSF Archives and Special Collections Intern.

Dear Reader, you may not be aware of the fact that most—if not all—archives must deal with the looming specter of unprocessed legacy collections haunting their vaults.  Hark, what’s that I hear?  The sound of researchers gnashing their teeth at the thought of virgin cartons, brimming with knowledge, just beyond their reach?  In the name of Science and History, what can be done?

Inside the UCSF Archives vault.

I’ll tell you good Reader!  An expedition is being undertaken at this very moment to survey those hidden but not forgotten boxes of lore that reside in the vault of the UCSF Archives. Possessing the requisite skills and patience, archivist David Uhlich and myself (your plucky and adroit, intern) are making our way through shelf after shelf of material – opening boxes, checking contents, and conferring with the notes of archivists gone by.

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Sometimes we find what’s on the shelf matches what information we have, but sometimes we come across half-created records or material lacking adequate description.  Despite these setbacks, we roll up our sleeves and soldier on, updating existing records with new information about content and location, or creating shiny new records of our own.

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It’s a long process, but it is important work.  Fear not, gentle Reader, for although the task seems Sisyphean in magnitude, the brave souls of the Archives and Special Collections are determined to succeed!

Digitizing the UCSF Black Caucus Records

This is a guest post by Jessica Jones, former UCSF Archives & Special Collections Intern.

As an intern for the UCSF Library, Archives and Special Collections, I have worked on many different projects that utilize my skills as a professional administrative assistant, including the State Medical Journals Digitization Project, a collection survey, rehousing and inventorying the portrait photograph collection, and more. I also attended Library Updates meetings and listened to presentations about changes within libraries. Although this was a very new experience to me I adapted very quickly and I am proud to say I have learned so much and have enjoyed my time here with UCSF.

I would like to share a bit more about my most recent project working with the Black Caucus records. I really found this project to be interesting; I researched, digitized, and uploaded material from the collection to the digital asset management system and assisted in creating original metadata to facilitate discovery of these items. You can now access the UCSF Black Caucus Records digital collection on Calisphere.

Black Caucus members at the first Gala, 1991

Black Caucus members at the first Gala, 1991

The Black Caucus was first established on the UCSF campus in May 1968 in the wake of the assassination of Dr. Martin Luther King, Jr.  This organization worked to provide more job opportunities for qualified minority applicants and lobbied for more minority students in all four professional schools. The organization engaged in many civil rights initiatives and social justice projects, like supporting custodial and technical staff in labor disputes and campaigning for more diverse hiring at all levels of the university. Beginning in the 1970s, the group shared personal stories, event updates, and project achievements in a newsletter named the Black Bulletin. There were many notable UCSF figures that helped found and lead the Black Caucus. For instance, UCSF Medal winner Joanne Lewis served as one of the organization’s first chairpersons and organized the publication of the Black Bulletin.

Black Bulletin, April 1978. Joanne Lewis: In retrospect.

Black Bulletin, April 1978. Joanne Lewis: In retrospect.

The Black Caucus records help to demonstrate that African Americans have contributed remarkable achievements in the fields of science and medicine during the 20th century. To encourage future researchers and clinicians of color I think that it is essential for boys and girls to be given the academic tools to succeed in science and medicine, preferably long before college. There are several programs that help facilitate this, such as the White House initiative “My Brother’s Keeper” that helps young people reach their full potential. Medical schools should also continue to sponsor pipeline programs to encourage minority students to consider careers in medicine.

Affirmative Action protest at Laurel Heights, 1995

Affirmative Action protest at Laurel Heights, 1995

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Jesse Jackson at Laurel Heights Affirmative Action protest, 1995

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Cecil Williams at Laurel Heights Affirmative Action protest, 1995

I am very proud and excited to be a part of this amazing project. The Black Caucus has helped support and encourage people of color at UCSF through advocacy and community. The organization’s message of equality shows how important it is to have a diverse population of practitioners to address healthcare needs and to eliminate racial and ethnic disparities in healthcare.

Internet Archive Partners Lunch

Friday the 13th of May was the auspicious date of our visit to one of our partner organizations, the Internet Archive, just across Golden Gate Park in the Richmond District. The Internet Archive is a non-profit digital library of millions of freely accessible books, movies, software, music, websites and more. Internet Archive graciously hosts a bi-weekly Partners Lunch, inviting anyone working in partnership with IA to tour the facility (a gorgeous re-purposed Christian Science church), meet staff in person, and participate in a lunchtime roundtable where IA folks and visitors share their projects’ progress, successes and failures. The whole UCSF Archives team, plus UCSF collections staff members Beatrice Mallek and David MacFarland, were in attendance.

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UCSF Archives and Special Collections staff with Internet Archive digitization staff.

We met with our IA liason Jesse Bell, who gave us a look into the progress of some of our projects ongoing at Internet Archive. Here Eliza Zhuang is using a specially designed scanning booth to digitize volumes of bound medical journals for the State Medical Journal project. The “scanner” actually uses two conventional DSLR cameras to simultaneously photograph the pages of the book, optimally positioned by the pedal-operated V-shaped glass plate shown here.

Eliza Zhuang scanning a medical journal from UCSF's collection.

Eliza Zhuang scanning a medical journal from UCSF’s collection.

After photography, the images undergo QA and metadata association before being uploaded to the Internet Archive, where they look like this.

IA’s lobby provides plenty of excitement. A prominently displayed monitor shows the digitization currently underway on a number of different systems. Below, David Uhlich watches as pages from the book scanner are photographed. Immediately behind the monitor is a film scanner that similarly feeds the live-view monitor. The lobby also houses a beautiful antique gramophone near a small listening station that includes an iPad loaded with digitized music and other recorded sound.

David Uhlich observes the progress of digitized images entering the system.

David Uhlich observes the progress of digitized images entering the system.

After lunch, we took a more in depth tour of IA’s facility. We saw an example of IA’s specially designed “portable” book scanner, which is basically a scaled-down version of the one used by IA staff. Approximately $10,000 will get you your own book scanning station, software, and support from IA for your own scanning projects. We also looked inside the refurbished church that, in addition to the pews, now houses some of IA’s servers and digitization equipment.

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Internet Archive servers occupy a niche.

Sculptures of miniature people inhabit the aisles.  Long-term IA staff are thanked for their service with a sculpture of their likeness; many depicted holding an item that reflects their interests or passions.

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Some of Internet Archive’s long-term staff immortalized in figurine form.

It was great to meet the IA team in person. Our partnership with IA continues to provide new opportunities to preserve and make accessible our material. We look forward to exciting projects in the future!

J. Michael Bishop Papers Online

We are pleased to announce that the J. Michael Bishop Papers digital collection is now available publicly on Calisphere.org. Bishop is a Nobel Prize-winning researcher and UCSF Chancellor Emeritus. The digital collection features hundreds of pages of material and photographs selected from Bishop’s papers housed in the UCSF Archives and Special Collections (MSS 2007-21).

J. Michael Bishop college portrait, Gettysburg College, circa 1955. MSS 2007-21, box 1, folder 4.

J. Michael Bishop college portrait, Gettysburg College, circa 1955. MSS 2007-21, box 1, folder 4.

J. Michael Bishop portrait with molecular model, circa 2000. MSS 2007-21, case D, folder 1.

J. Michael Bishop portrait with molecular model, circa 2000. MSS 2007-21, case D, folder 1.

J. Michael Bishop, MD, joined the UCSF faculty in 1968. He was appointed director of the GW Hooper Research Foundation in 1981 and named UCSF Chancellor in 1998, a post he held until 2009. He continues to serve as Hooper’s director and as professor in the Department of Microbiology and Immunology.

 J. Michael Bishop email to Harold Varmus regarding Bishop's University of California, San Francisco Chancellor appointment, 1998-02-06. MSS 2007-21, carton 18, folder 43.

J. Michael Bishop email to Harold Varmus regarding Bishop’s University of California, San Francisco Chancellor appointment, 1998-02-06. MSS 2007-21, carton 18, folder 43.

In 1989, Bishop and his research partner, Harold Varmus, were awarded the Nobel Prize in Physiology or Medicine for their work in cancer research. Bishop and Varmus discovered the cellular origin of retroviral oncogenes. Their work helped clarify the processes that convert normal cellular genes into cancer genes and impacted our understanding of the genesis of human cancer.

J. Michael Bishop and Harold Varmus at Nobel Shindig, a county-western themed dinner party given by Varmus and Bishop in celebration of their Nobel Prize award in Physiology or Medicine; held at DeMarco's 23 Club, Brisbane, California, 1989. MSS 2007-21, carton 8, folder 41.

J. Michael Bishop and Harold Varmus at Nobel Shindig, a county-western themed dinner party given by Varmus and Bishop in celebration of their Nobel Prize award; held at DeMarco’s 23 Club, Brisbane, California, 1989. MSS 2007-21, carton 8, folder 41.

The digital collection features selections from Bishop’s laboratory research notebooks and professional papers, including article drafts, correspondence with other scientists, and teaching and lecture material. Also included are photographs and draft figures created by Bishop for his publications.

Purification of Annealed Product Gd RNA graphs. Selected page from a laboratory research binder of J. Michael Bishop, circa 1970. MSS 2007-21, carton 18, folder 3.

Purification of Annealed Product Gd RNA graphs. Selected page from a laboratory research binder of J. Michael Bishop, circa 1970. MSS 2007-21, carton 18, folder 3.

The Life Cycle of Rous Sarcoma Virus diagram drawing (1) by J. Michael Bishop; created for Bishop's article "Oncogenes" published in Scientific American, 1982. mss200721_2_2_sciamerican1.

The Life Cycle of Rous Sarcoma Virus diagram drawing (1) by J. Michael Bishop; created for Bishop’s article “Oncogenes” published in Scientific American, 1982. MSS 2007-21, carton 2, folder 2.

You can view the digital collection on Calisphere.org. If you would like to visit the UCSF Archives and work with the complete physical collection, please check out the detailed inventory available on the Online Archive of California and make an appointment with us.

Upcoming Lecture: Heightened Expectations

Date: Tuesday, May 17th, 2016
Time: 12 pm – 1:15 pm
Lecturer: Aimee Medeiros, PhD (UCSF)
Location: Lange Room, 5th Floor, UCSF Library – Parnassus
530 Parnassus Ave, SF, CA 94143
This event is free and open to the public. Light refreshments will be provided.

REGISTRATION REQUIRED: http://calendars.library.ucsf.edu/event/2544252

Join UCSF Archives & Special Collections for an afternoon talk with author Aimee Medeiros as she discusses her book Heightened Expectations: The Rise of the Human Growth Hormone Industry in America.

Heightened Expectations: The Rise of the Human Growth Hormone Industry in America

Heightened Expectations is a groundbreaking history that illuminates the foundations of the multibillion-dollar human growth hormone (HGH) industry. Drawing on medical and public health histories as well as on photography, film, music, prose, and other examples from popular culture, Aimee Medeiros tracks how the stigmatization of short stature in boys and growth hormone technology came together in the twentieth century. Historical materials from the UCSF Archives collection were used in the research for this book.

Aimee Medeiros, PhD

Aimee Medeiros, PhD

Aimee Medeiros is an assistant professor of the history of health sciences at the University of California, San Francisco.

About the UCSF Archives & Special Collections Lecture Series
UCSF Archives & Special Collections launched this lecture series to introduce a wider community to treasures and collections from its holdings, to provide an opportunity for researchers to discuss how they use this material, and to celebrate clinicians, scientists, and health care professionals who donated their papers to the archives.

UCSF Archives Coloring Book

We created a coloring book featuring illustrations from fifteenth to nineteenth-century rare books housed in the UCSF Archives and Special Collections. Coloring reduces stress, inspires creativity, and it’s just plain fun. You can scroll through a few of the images below and download the entire book for free here. Happy coloring!

We would love to see your finished creations. Tweet your pictures @ucsf_archives and use #ColorOurCollections.

Ketham, Joannes de. The Fasciculo di medicina, Venice. 1493. Find it at the UCSF Library: ucsfcat.library.ucsf.edu/record=b1121554~S0

Ketham, Joannes de. The Fasciculo di medicina, Venice, 1493. ucsfcat.library.ucsf.edu/record=b1121554~S0

Konrad, von Megenberg. Buch der Natur. 1482. Find it at the UCSF Library: ucsfcat.library.ucsf.edu/record=b1074494~S0

Konrad, von Megenberg. Buch der Natur, 1482. ucsfcat.library.ucsf.edu/record=b1074494~S0

Ryff, Walther Hermenuis. Omnium humani corporis partium… 1541. Find it at the UCSF Library: ucsfcat.library.ucsf.edu/record=b1063757~S0

Ryff, Walther Hermenuis. Omnium humani corporis partium…, 1541.
ucsfcat.library.ucsf.edu/record=b1063757~S0

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Bartisch, Georg. Ophthalmodouleia. 1583. ucsfcat.library.ucsf.edu/record=b2286634~S0

Download the complete UCSF Archives and Special Collections Coloring Book

Early MRI technology on display now at the UCSF Library

The UCSF Archives and Special Collections is pleased to announce the opening of a new exhibit at the UCSF Library, Vision for the Future: Advancing MRI Technology at UCSF’s Radiologic Imaging Laboratory, 1975-2000. The exhibit explores the pivotal role UCSF researchers played in developing imaging technology that revolutionized patient care and transformed the way we see our bodies. View material from the Radiologic Imaging Laboratory records housed in the UCSF Archives, including research notebooks, MRI coil prototypes, rare photographs, and more.

Join us April 5th at 12 noon for the exhibit’s official opening. Archivists will be on hand to answer any of your questions!

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MRI scale model and coil prototype on display.

The Radiologic Imaging Laboratory (RIL) was founded in the mid-1970s by a team of UCSF scientists and engineers. Their goal was to create a clinically viable diagnostic tool using nuclear magnetic resonance imaging, later called MRI. Over the course of 25 years, the lab brought together venture capitalists, researchers, and clinicians to develop, evaluate, and market new imaging systems and instruments. The lab’s interdisciplinary approach and partnerships with private corporations, including Pfizer, Diasonics, and Toshiba, led to rapid innovation and numerous patents that continue to impact clinical care today.

Lab researchers and technicians Lawrence Crooks, Bob McCree, Ian Duff, and Roger Littlewood, circa 1981. Photograph collection.

RIL researchers and technicians Lawrence Crooks, Bob McCree, Ian Duff, and Roger Littlewood, circa 1981. Photograph collection.

The exhibit showcases just a fraction of the over 90 linear feet of engineering records, correspondence, and other material in the collection (call number MSS 2002-08). Through the generous support of RIL engineer, Dr. Lawrence E. Crooks, the UCSF Archives has processed the collection and created a detailed inventory available to researchers on the Online Archive of California. Archives staff have also made hundreds of documents and photographs from the collection available digitally on Calisphere, a public online portal.

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MRI coil on display.

The exhibit is located on the main floor (3rd floor) of the UCSF Library, 530 Parnassus Ave. It is free and open to the public during Library hours, April 2016-April 2017.

New Interns in Archives

During the 2016 Spring semester the UCSF Archives & Special Collections is hosting two interns:

Jessica Jones

Jessica JonesJessica Jones is our first EXCEL program intern. The UC San Francisco Excellence through Community Engagement & Learning (EXCEL) Program is a clerical/administrative training program which aims to develop the potential workforce in UCSF’s surrounding communities and provide San Francisco residents with access to health-field related employment opportunities. It is a work-based  program that uses both classroom and on-the-job training to prepare participants for career path jobs in the healthcare sector. In the past month Jessica who works in the Archives  four days a week has successfully completed the State Medical Society Journals assessment  and Cholera pamphlets cataloging projects. She is working on rehousing and creating detailed inventory for the Photo Portraits collection which will help preserve these photographs and facilitate their discovery. Jessica will help organize, rehouse and create inventories for newly acquired papers and also learn how to scan and create metadata for materials in diverse formats.

Here is what Jessica wrote for the blog: “I am a mother of two beautiful children ages 1 and 4. I am a San Francisco native and a current intern through the EXCEL Cycle 10 UCSF Medical Administrative Internship. After becoming a mother I realized what I was inspired and motivated by. I have many talents and desires but my main four passions in life are Children, Happiness, Self Love, and Fashion. Due to my natural spirit to connect and adapt with people so well I have a goal to become a professional as a Clinical Social Worker in Pediatrics. I am one step closer to my future by getting my foot in the door within my internship at UCSF.  I plan to reach out and advocate for families that lack social and emotional support. I want to make a difference within children and actually give and instill in them extra love, support, and mentoring . Currently I am interning for the Archives and Special Collections, I plan to enrich my own knowledge and gain plenty experience to become an unparalleled asset. I also plan to look into the development of pediatrics department within UCSF. Finally, I am so thankful for this amazing opportunity. My dream is becoming a reality.”

Kristin Daniel

Kristin DanielKristin Daniel first became interested in library science when she was young; when her curiosity, more often than not, led her to find answers in books.  The importance of information availability stayed with her throughout her schooling.  Her passion was put on hold after she graduated high school in 1998, as economic necessities led her to a decade of service in the retail and hospitality industries.  She got the opportunity to return to school and pursue her dream in 2008.

She graduated cum laude from San Francisco State University with a Bachelor’s Degree in English Literature and is currently in her last semester of San Jose State University’s iSchool Masters in Library and Information Science program.  Her coursework at SJSU reflects her interest in public librarianship with an emphasis in archives and preservation.  Kristin is hopeful that she can serve her community’s information needs with the skills she can learn at her internship at UCSF: practical experience in cataloging, collection processing, and digitization.  With so many people turning to digital means of finding information she is a firm proponent of a global library network.

Between being a stay-at-home-mom and a full time grad student, Kristin doesn’t have a lot of time for hobbies.  When she can find a few moments to relax, however, she can usually be found reading sci-fi/fantasy novels, exploring San Francisco’s numerous events/attractions, and daydreaming about winning the lottery so she can build a craft studio.  A lifelong California resident, Kristin currently resides in San Ramon with her husband and two-year-old son.

Kristin is continuing the project started by previous interns – organizing and creating an inventory of biographical files. She also helps with Quality Control of digital files for the State Medical Society Journals project.

Both Jessica and Kristin are assisting with the survey of the Archives and Special Collections manuscript and university records collections. The inventory and reorganization of these collections will greatly increase intellectual control, department efficiency, and user access.

We are grateful to our interns for their dedication and help!