Upcoming Lecture & Exhibit: History, Science and Art of Ocular Prosthetics

Lecture & Opening Reception
May 28, 2015,  3 – 5 pm
Lecturer: Robert S. Sherins, MD (UCSF, School of Medicine, Class of 1963)
This event is free and open to the public. Light refreshments will be provided.
REGISTRATION REQUIRED: tiny.ucsf.edu/lecture528
Lange Room, 5th Floor, UCSF Library – Parnassus
530 Parnassus Ave, SF, CA 94143

According to the United States Eye Injury Registry, each year there are more than 2.5 million eye injuries, from which 50,000 people permanently lose all or part of their vision, often leaving them severely disfigured. Through the centuries there had been many attempts to create safe, cosmetically pleasing and comfortable ocular prostheses. However, past devices were not designed well enough, fit poorly due to the gross sizing of the prosthetic samples and most of them were certainly irritating due to the use of unsuitable materials that were available at the time.

Illustrations for Hypoblephara (top) and Ekblephara from a book by Ambroise Paré, "The workes of that famous chirurgion Ambrose Parey...," 1649.The digital copy of othis book is accessible online through the Medical Heritage Library: https://archive.org/details/workesofthatfamo00par.

Illustrations for Hypoblephara (top) and Ekblephara from a book by Ambroise Paré, “The workes of that famous chirurgion Ambrose Parey…,” 1649, p. 576-577. The digital copy of this book is accessible online through the Medical Heritage Library and the original can be viewed at the UCSF archives.

Often called the “father of ocular prosthesis,” French surgeon Ambroise Paré in 16th century invented a device (Ekblephara) consisting of a leather-covered metal base with a painted eye, lid and lashes that was worn over the eyelid. Later on, Paré developed a metal accessory (Hypoblephara eye) that was inserted under the eyelid into the socket over the remaining atrophic eye.

Ludwig Müller-Uri (center) with his sons Albin and Reinhold, ca. 1875.  Courtesy of Museum of Glass Art Lauscha.

Ludwig Müller-Uri (center) with his sons Albin and Reinhold, ca. 1875. Courtesy of Museum of Glass Art Lauscha.

Modern methods of creating ocular prostheses can be traced to the ingenuity of Ludwig Müller-Uri, a Glasbläser (glassblower) from Lauscha, Province of Thuringia, Germany. The town’s craftsmen also were known for their Christmas glass decorations, glass marbles, utilitarian housewares and doll’s eyes. After training with Prof. Heinrich Adelmann, an ophthalmologist in Würzburg, Müller-Uri became an “Augenprothetik” (prosthetic eye-maker) or ocularist. He improved the artificial eyes by individually fitting each prosthetic. Müller-Uri created the iris details using special tools to apply the pigments he blended to most realistically resemble the natural eye. By 1835, he began using a better quality glass from the local factory. It was not until 1885 that the best cryolite glass became available, which was crucial for the patient’s tolerance of the prosthesis since they became lightweight, corrosion-resistant and more lifelike. It became the standard material for making ocular prosthetics and is still used in Germany, whereas acrylic plastic has replaced cryolite glass in the U.S.
The Müller-Uri family working with the ophthalmologist from the Netherlands, Hermann Snellen designed the “Snellen eye” or “Reform-Auge” (“reform eye”) – prosthesis that consists of two connected shells with a hollow space between them and that can be worn by a patient with the enucleated eye.

Left to right: ocularists: Phillip Danz of Sacramento and William Danz of San Francisco, and Dr. Robert Sherins, ophthalmologist, UCSF School of Medicine Alumnus Class of 1963 holding the Danz collection of ocular pathology specimens during their visit to the UCSF Archives and special Collection in January, 2015.

Left to right: ocularists: Phillip Danz of Sacramento and William Danz of San Francisco, and Dr. Robert Sherins, ophthalmologist, UCSF School of Medicine Alumnus Class of 1963 holding the Danz collection of ocular pathology specimens during their visit to the UCSF Archives and Special Collections in January, 2015.

During the 1880s, Amandus Müller manufactured approximately 13 eye-kits consisting of ocular pathology specimens – the hand-blown glass eye models depicting diseases. He sold the kits to European medical schools where they were used as teaching aids. Amandus Müller was a grand uncle of Gottlieb Theodore Danz, Sr. In 1915, Gottleib T. Danz, Sr. immigrated with his family to New York and brought one of his uncle’s kits to America. Later on, he moved his office to San Francisco. After the death of Gottlieb T. Danz, Sr., his widow gave that kit to her grandson, Phillip Danz (also an ocularist). In 1963, Phillip donated the kit to Professor Michael Hogan, MD, then Chairman of the UCSF Ophthalmology Department. Eventually the kit was given to the UCSF Archives, where it remains preserved today.

Specimen #34 from the Danz ocular pathology collection.

Specimen #34 from the Danz ocular pathology collection. It shows massive traumatic scleral and corneal lacerations, dislocation of the entire lens, severe inflammation and herniation of the vitreous gel.

This beautiful collection was exhibited several times during the past 50 years. However, many historic details about this donation were lost. The purpose of the upcoming lecture and comprehensive exhibit is to use this unique artifact to tell the story of family traditions continued through the centuries on two continents. Through partnership with several members of the Danz family – ocularists: Phillip Danz of Sacramento; William Danz of San Francisco; and William Randy Danz of Ridgewood, New Jersey; as well as the author/lecturer, Dr. Robert Sherins, ophthalmologist, UCSF School of Medicine Alumnus Class of 1963; and UCSF archivist, Polina Ilieva, this exhibit will demonstrate the evolution of skillful craftsmanship of Müller-Uri and Danz families, as well as the science and art of ocular prosthetics. The UCSF Library is grateful to the Danz Family and Dr. Sherins for their continuing support.

Happy National Library Week!

In observance of this lovely celebratory week, we bring you a few images of UCSF Library staff and librarians in their natural habitat from the 1950s.

 

photocoll_buildings_medicalsciencesbldg_library5

Photograph collection, Medical Sciences Building – The Library

Above, the entrance way to the old UCSF Library, in the Medical Sciences building, in 1959. Check out our previous post that expands a bit on the history of that library.

 

photocoll_buildings_medicalsciencesbldg_library3

Photograph collection, Medical Sciences Building – The Library

Tidying the current periodicals section in the 1950s.

 

photocoll_buildings_medicalsciencesbldg_library4

Photograph collection, Medical Sciences Building – The Library

Librarians of the Catalog Department (note card catalogs in the background) in the fall of 1958.

 

Lecture now online – The Forgotten Epidemic: HIV/AIDS in Women and Children

The lecture The Forgotten Epidemic: HIV/AIDS in Women and Children given by Dr. Arthur Ammann in the UCSF Library on February 26th is now available free online.

IMG_2928_ebolalessons

Beginning in 1981 researchers at UCSF defined some of the most important features of the emerging AIDS epidemic – the cause of AIDS, the clinical features of AIDS, populations at risk for HIV infection, methods to prevent and treat HIV, and discovery of HIV. Working closely with community activists, advocates, scientists and policy makers, UCSF distinguished itself as a model of successful collaboration. The first discovery of AIDS in infants and children and blood transfusion associated AIDS at UCSF were instrumental in defining the extent of the epidemic. The scientific advances in HIV/AIDS that occurred over the next two decades were remarkable resulting in the near eradication of HIV in infants in the US and transforming an acute and fatal infection in adults to a chronic and manageable one. But even as these advances occurred benefiting many millions of people worldwide, women and children were too often excluded, resulting in a global epidemic that is now composed of over 50% women and children and a secondary epidemic of AIDS-related orphans that numbers in the tens of millions.

Please use this link to view Dr. Ammann’s presentation in full.

About the UCSF Archives & Special Collections Lecture Series
UCSF Archives & Special Collections launched this lecture series to introduce a wider community to treasures and collections from its holdings, to provide an opportunity for researchers to discuss how they use this material, and to celebrate clinicians, scientists, and health care professionals who donated their papers to the archives.

Collections in the Media

We’re proud to tell you about two new documentaries that used material from our collections and are hitting screens big and small near you.

Ken Burns’ new 3-part documentary, Cancer: The Emperor of All Maladies, premieres on PBS tonight, March 30. The film “examines cancer with a cellular biologist’s precision, a historian’s perspective and a biographer’s passion. The series artfully weaves three different films in one: a riveting historical documentary; an engrossing and intimate vérité film; and a scientific and investigative report.” It’s based on the book written by physician and oncologist Siddhartha Mukherjee and published in 2010, described as a “biography of cancer.”

[Note for UCSF Library fans: Mukherjee is married to Sarah Sze, the artist who created the mirror polished stainless steel sculpture in the front stairwell of the Parnassus library.]

[iframe width=”560″ height=”315″ src=”https://www.youtube.com/embed/MDsqTGJ9lYo” frameborder=”0″ allowfullscreen]

 

The film Merchants of Doubt, by the filmmakers of Food, Inc., is now playing in theaters in San Francisco (and elsewhere). It’s “the troubling story of how a cadre of influential scientists have clouded public understanding of scientific facts to advance a political and economic agenda.” The team was on-site for several days, interviewing UCSF Professor Stan Glantz in our reading room and filming in the vault.

[iframe width=”560″ height=”315″ src=”https://www.youtube.com/embed/j8ii9zGFDtc” frameborder=”0″ allowfullscreen]

 

Let us know if you’re able to see either film! What did you think?

And, of course, contact us anytime via our online contact form to submit a question or comment. You can also email us directly at libraryarchives@ucsf.edu.

New TCA Archivist

David Krah

David Krah

David Krah joins UCSF to work on processing collections in the Tobacco Control Archives. He will work alongside David Uhlich on processing state reports on tobacco control policy as well as the balance of unprocessed collections held in the Tobacco Control Archives.

David has a Masters Degree in Library and Information Science from San Jose State University, with a concentration in Archival Studies. He has worked on archival projects with the California Historical Society, the San Francisco Public Library, San Francisco Public Utilities Commission, the Road & Track Magazine collection at Stanford University, and previously worked on the Ira Herskowitz papers and Lawrence Crooks Radiologic Imaging Laboratory records at UCSF.

He is a native Californian with interests in California history and transportation and livability issues. He enjoys composing and performing experimental and song-form music and cycling jauntily. He lives in San Francisco with his wife Nia and newborn daughter Thalia.

Tobacco Control Archive Processing Project

David Uhlich

David Uhlich

The UCSF Archives recently received funding from the Center for Tobacco Control Research and Education to catalog and process the Tobacco Control Archive collections and in particular the state reports materials that were compiled by Dr. Stanton Glantz’ research group while completing detailed histories of tobacco control policymaking and efforts by the tobacco industry to thwart these policies in 29 states.

Today I would like to introduce David Uhlich who just joined the archives team and will be working on the TCA processing project.

David holds a Master’s degree in Library and Information Science from San Jose State University, and for the past 6 years has worked for the Bancroft Library at the University of California, Berkeley. At the Bancroft, he was primarily responsible for processing political collections, and most recently led the project to process the papers of Governor Edmund G. “Pat” Brown.

Prior to this, David worked as an archivist at the Water Recourses Center Archives, the Charles M. Schulz Museum and Research Center, and the Tomales Regional History Center. He is a Certified Archivist and active member of the Society of California Archivists, where he currently serves as the Northern California chair of the Site Selection Committee.

David is a lifelong Californian, and for the past 8 years has lived in Marin County with his wife and two very large dogs.

Viewing Zakheim Murals at UCSF

As part of UCSF’s 150th anniversary celebration, the university has arranged special public viewing hours for the Zakheim murals through the spring:

Friday, March 13th:  4 – 7 p.m.
Friday, April 17th:  3 – 5 p.m.
Friday, May 22nd:  3 – 5 p.m.

Location:
Toland Hall on the UCSF Campus
533 Parnassus Ave., Room U-142
San Francisco, CA
Map of UCSF Parnassus Campus and Directions (printable PDF)

Recent article in San Francisco Chronicle highlights history of the Zakheim murals at UCSF.

Do you have questions or need additional information about public viewing?
Please contact UCSF Public Affairs: 415-476-2557

Early MRI Scans

We’re currently processing the Radiologic Imaging Laboratory records, 1968-2000. The collection contains numerous images of magnetic resonance imaging (MRI) scans. The images help document the lab’s achievements in MRI research and illustrate dramatic developments in the technology.

MRI head scan from a patient logbook, 1986, MSS 2002-08. The image is from a Polaroid photograph of a computer screen.

MRI head scan from a patient logbook, 1986. The image is from a Polaroid photograph of a computer screen. MSS 2002-08

MRI scan images come in several formats in the collection. These include marketing prints and slides, transparent film sheets and negatives, and Polaroid photographs. Lab researchers used Polaroid cameras to capture images on computer screens created by in-development software and hardware.

MRI head scan from a patient logbook, 1988, MSS 2002-08. The image is from a Polaroid photograph of a computer screen.

MRI head scan from a patient logbook, 1988. The image is from a Polaroid photograph of a computer screen. MSS 2002-08

Several of the laboratory notebooks in the collection contain Polaroid photographs fastened right to the page, with research notes and data surrounding them.

Laboratory notebook of Lawrence Crooks with scan images, 1983. MSS 2002-08

Laboratory notebook of Lawrence Crooks with scan images, 1983 (subject’s name redacted). MSS 2002-08

As you move chronologically through the collection, you can see the MRI scans becoming clearer and clearer as lab researchers improved the technology. You can also chart changes in the lab’s research subjects. Image subjects transition from phantom objects (containers often filled with baby oil and water) to lab animals and RIL staff and patients.

Prints prepared for a 1985 Diasonics/RIL sales meeting. MSS 2002-08

Prints prepared for a 1985 Diasonics/RIL sales meeting. MSS 2002-08

Though the images present preservation challenges, they contribute greatly to the research value of the collection. Using the scans, you can witness the lab’s growth through different phases of MRI research and development.

Recent Acquisition: Bernard Zakheim Collection

Ever since the Polish-born artist Bernard Zakheim painted a series of murals at UCSF in 1930s they remain the jewel of the University’s Art Collection. These murals include ten panel series in Toland Hall, “History of Medicine in California,” and two panels originally located in the Cole Hall and later moved to the Health Sciences West (HSW) lecture halls – “Modern Medicine” and “Ancient Medicine: Superstition in Medicine.” Zakheim worked with Diego Rivera in Mexico City and is best known for contributing the Library Periodical Room fresco and helping organize the New Deal art project at the Coit Tower in San Francisco. From the time of their unveiling, the archives has been compiling reference materials about these murals and now we are delighted to report that a comprehensive set of materials documenting how these frescoes were created and preserved was donated to UCSF (Bernard Zakheim collection, MSS 2014-15).

Viewing murals at Toland Hall at UCSF, left to right: F. Stanley Durie, Superintendent of UC Hospital, Dr. William E. Carter, Phyllis Wrightson, Joseph Allen, State Director of WPA Federal Art Project, Bernard Zakehim (ca. 1939)

Viewing murals at Toland Hall at UCSF, left to right: F. Stanley Durie, Superintendent of UC Hospital, Dr. William E. Carter, Phyllis Wrightson, Joseph Allen, State Director of WPA Federal Art Project, Bernard Zakehim (ca. 1939)

Last year I had the privilege to meet one of the sons of the artist who also helped restore the frescoes in 1970s when the wallpaper covering them for almost two decades was removed and the two panels were relocated from the original Cole Hall to HSW.

Artist Bernard Zakheim with his son Nathan Zakheim (1967)

Artist Bernard Zakheim with his son Nathan Zakheim (1967)

One of the biggest archives’ advocates, Dr. Robert Sherins (SOM, 1963) introduced me to Nathan Zakheim. Nathan, a talented art conservator based in Los Angeles, is the keeper of his father’s extensive archives and art collection. Last fall we met at his warehouse to review and pack the documents destined for UCSF.

The idea to commission murals was brought by Dr. Isabella Perry, professor of pathology after seeing the frescoes Zakheim painted at the Alemany Public Health Center and then spearheaded by Chauncey D.  Leake, professor of pharmacology and medical historian. The university murals undertaking which was partially funded by the WPA Federal Art Project and also sponsored by the university was a true collaborative effort between Zakheim’s team and UCSF faculty (including renowned UCSF doctors,  Chauncey D. Leake, George Lyman, Langley Porter, Salvatore P. Lucia, W. E. Carter, and F. W Lynch). The artist was provided unrestricted access to the Crummer Room containing numerous books on the history of medicine, including recently published “California’s Medical Story” by Dr. Henry Harris. Zakheim’s assistant, Phyllis Wrightson did extensive research about California medical history which becomes apparent in the sketchbook that she kept for the project. The instruments depicted by her on these pages are still preserved at the archives’ artifact collection and will be displayed as part of the 150th anniversary exhibit.

Drawings of surgical instruments from the UCSF collection for the panel devoted to Don Pedro Prat, surgeon of the Portolá expedition.

Drawings of surgical instruments from the UCSF collection for the panel devoted to Don Pedro Prat, surgeon of the Portolá expedition.

Surgeon Don Pedro Prat treats patient’s leg, James Ohio Pattie vaccinates Californians.

Surgeon Don Pedro Prat treats patient’s leg, James Ohio Pattie vaccinates Californians.

One of the sketches portrays fur trader James Ohio Pattie who was captured for illegal trapping in California and earned his release from Mexican imprisonment in San Diego by using the smallpox vaccine to curtail the epidemic spreading among Californians (that story based on the Pattie’s “Personal Narrative” was later proved to be inaccurate as it was measles epidemic* that occurred in Alta California at that time).

Bernard Zakheim at work, 1937

Bernard Zakheim at work, 1937

Drawing of James Ohio Pattie.

Drawing of James Ohio Pattie.

Bernard Zakheim and his team interviewed numerous faculty members who are depicted in the panel “Rational Medicine,” including Robert Stone, professor of radiology, Francis S. Smith, pediatrician and dean of the School of Medicine, Karl F. Meyer, director of the Hooper Foundation, anesthesiologist Arthur Guedel and Isabella Perry to name just a few.

Scaffoldings in the original Cole Hall (that was located at the School of Medicine building) set up while Bernard Zakheim was working on the panel “Rational Medicine.”

Scaffoldings in the original Cole Hall (that was located at the School of Medicine building) set up while Bernard Zakheim was working on the panel “Rational Medicine.”

We are grateful to the Zakheim family and in particular to Nathan Zakheim for donating this unique collection to the University. It will be organized and described in the next few months, selected slides and documents will be digitized and uploaded to the library website.
Are you interested in viewing the murals, but unable to visit San Francisco? Please check these two video recordings from the UCSF archives:
Dr. Robert Schindler (Chair emeritus of the UCSF Department of Otolaryngology) presents a video tour of the murals painted by Bernard Zakheim in Toland Hall at UCSF, 1996: https://archive.org/details/cum_00001
Toland Hall murals tour by Dr. Chauncey Leake, 1976: https://archive.org/details/cum_000015

We would also like to bring to your attention a manuscript put together by Dr. Sherins chronicling the life story and work of Bernard Zakheim that can be accessed on the Alumni Association website.


* Valle, Rosemary K. “James Ohio Pattie and the 1827-1828 Alta California Measles Epidemic.” California Historical Quarterly, Vol. 52, No. 1 (Spring, 1973), pp. 28-36, http://www.jstor.org/stable/25157415.

UCSF Archives Lecture: The Forgotten Epidemic: HIV/AIDS in Women and Children

Join us on Thursday, February 26th as Arthur Ammann, M.D., gives a lecture in a series launched by UCSF Archives & Special Collections.

Date: Thursday, February 26th, 2015
Time: 4 pm-5:20 pm
Location: Lange Room, UCSF Library, 530 Parnassus, 5th floor
This lecture is free and open to the public. Light refreshments provided.
Please RSVP to reserve a seat

Collage of lab data on first patients in 1981, MMWR report and 1982 San Francisco Chronicle article on first blood transfusion AIDS

Collage of lab data on first patients in 1981, MMWR report and 1982 San Francisco Chronicle article on first blood transfusion AIDS

Beginning in 1981 researchers at UCSF defined some of the most important features of the emerging AIDS epidemic – the cause of AIDS, the clinical features of AIDS, populations at risk for HIV infection, methods to prevent and treat HIV, and discovery of HIV. Working closely with community activists, advocates, scientists and policy makers, UCSF distinguished itself as a model of successful collaboration. The first discovery of AIDS in infants and children and blood transfusion associated AIDS at UCSF were instrumental in defining the extent of the epidemic. The scientific advances in HIV/AIDS that occurred over the next two decades were remarkable resulting in the near eradication of HIV in infants in the US and transforming an acute and fatal infection in adults to a chronic and manageable one. But even as these advances occurred benefiting many millions of people worldwide, women and children were too often excluded, resulting in a global epidemic that is now composed of over 50% women and children and a secondary epidemic of AIDS-related orphans that numbers in the tens of millions.

Arthur J. Ammann, M.D.

Arthur J. Ammann, M.D.

Arthur J. Ammann, M.D., is a founder of Global Strategies, a nonprofit organization that serves women and children in the most neglected areas of the world and Clinical Professor of Pediatrics at UCSF.
From 1971 to 1985, Dr. Ammann was Director of Pediatric Immunology and Clinical Research Center at the UCSF Medical Center, San Francisco. In 1977, Dr. Ammann’s clinical trials of a pneumococcal vaccine resulted in the first FDA approval of a vaccine for bacterial pneumonia and meningitis in children and adults. In 1982 Dr. Ammann described two of the three ways that HIV is transmitted including the first cases of transmission of AIDS from mother to infant and the first blood transfusion associated AIDS patients.
Dr. Ammann has received honors from more than 60 national and international organizations including the United States Surgeon General Award for Research and Heroes in Medicine Award by the International Association of Physicians in AIDS Care.
Dr. Ammann has authored over 300 scientific papers which have appeared in major medical journals. He holds a Bachelor of Science degree in biology from Wheaton College (1958) and a doctor of medicine degree from New Jersey College of Medicine (1962).  He received residency training from the department of pediatrics at UCSF and fellowship training in immunology from the University of Minnesota Medical Center and the University of Wisconsin Medical Center.
Dr. Ammann’s oral history,“Pediatric AIDS Immunologist: Advocate for the Children” is accessible online and at the UCSF Library.

About the UCSF Archives & Special Collections Lecture Series
UCSF Archives & Special Collections launched this lecture series to introduce a wider community to treasures and collections from its holdings, to provide an opportunity for researchers to discuss how they use this material, and to celebrate clinicians, scientists, and health care professionals who donated their papers to the archives.